That I own personally......5 I'm getting ready to buy 17 more from a friend who bought a bunch he thought he could flip and is now stuck with.
Most of them I'll probably just let sit for now. A couple I'll build websites for and develop. I know companies that own 100 or more domains. Managing them isn't an issue as you make sure they are paid up to date and move on to more important matters.
I have a total of 22 domain names that are registered with Rsdarkness.com. I use them for personal & business use. Management of the domain names is pretty easy because I have them all under my VPs (Virtual Private Server) Account. Design-Wise, I built the sites using a range of Content Management Systems (Wordpress, Joomla, GeekLog) and update as and when required. Best Regards, Michael James Swan Twitter: @mike_swan
Many would say to keep your domains and your hosting separate for various reasons such as, If you got behind on your hosting for any reason (loss of income ect) your domain will probably not be released to you till you come current on your bill. Also if your host goes belly up its a major headache to go through ICANN to prove that you paid. It really depends on how much you trust your host. More then half of our hosting clients also have their domains registered with us and there's not been any problems.
I have a great amount of trust in the company that hosts my websites. I have been with them since 2007, and never had an issue. All downtime has been planned and even then it was very minimal; where they used a spare server to keep the sites online. (Just the brief few minutes of downtime).